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Dok-2(Phospho Tyr299) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification which negatively regulates cell proliferation

SKU: 46080062408

4.2
DKK111.00 DKK149.00

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Dok-2(Phospho Tyr299) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification which negatively regulates cell proliferationThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Description

which negatively regulates cell proliferation

The tripartite motif containing 38 contains a RING-type zinc finger

may reduce overall tumorigenic potential

The encoded protein interacts with the C-terminal domain of ezrin| an ERM protein| and may play a role in cell adhesion and migration

observation and labeling

Dok-2(Phospho Tyr299) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification which negatively regulates cell proliferationThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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