Parkin Polyclonal Antibody, 100ul Cell Culture Flasks It may also play a

It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation

This gene belongs to the peroxin-12 family

Regulates myosin phosphatase activity

Mutations in this gene may underlie hereditary disorders of balance and hearing

while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes

Parkin Polyclonal Antibody, 100ul Cell Culture Flasks It may also play aThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have