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SFRP1 Polyclonal Antibody, 100ul Vessels This gene plays a role

SKU: 45896123070

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SFRP1 Polyclonal Antibody, 100ul Vessels This gene plays a roleThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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Description

This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity

This gene is a candidate for the ovarian tumor suppressor gene

It has been suggested that defects in the human gene result in pipecolic acidemia

including autoimmune diseases

PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3

SFRP1 Polyclonal Antibody, 100ul Vessels This gene plays a roleThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

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