T3HPD Rabbit Polyclonal Antibody, 50ul ADME Mutations in this gene may

Mutations in this gene may play a role in familial idiopathic basal ganglia calcification

|Contains 1 Rho-GAP domain

catalyzing the production of cGMP from GTP

It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling

BUB3 encodes a protein involved in spindle checkpoint function

T3HPD Rabbit Polyclonal Antibody, 50ul ADME Mutations in this gene mayThe protein encoded by this gene is a dehydratase that converts trans 3 hydroxy L proline to delta(1) pyrroline 2 carboxylate. This enzyme may function to degrade dietary proteins that contain trans 3 hydroxy L proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site.