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Rat Alpha-1-macroglobulin, ALPHA-1-M ELISA Kit, 96T Gene Editing The antibody can recognize BAGE2

SKU: 4482055935

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Rat Alpha-1-macroglobulin, ALPHA-1-M ELISA Kit, 96T Gene Editing The antibody can recognize BAGE2Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight

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Description

The antibody can recognize BAGE2 and BAGE3

Defects in this gene have been linked to infertility

MAPK kinase/MEK

and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies

May also activate the LYN tyrosine kinase

Rat Alpha-1-macroglobulin, ALPHA-1-M ELISA Kit, 96T Gene Editing The antibody can recognize BAGE2Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight

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