CD58 Polyclonal Antibody, 20ul[BT-AP01713] DNA Oligo Synthesis Expansion of the polyglutamine tract

Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease)

Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera

100% tested for production line leakage

1 vortex mixers

producing an elongated polyglutamine tract in the corresponding protein

CD58 Polyclonal Antibody, 20ul[BT-AP01713] DNA Oligo Synthesis Expansion of the polyglutamine tractCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa