POLR3B Polyclonal Antibody, 20ul Mammalian Expression and it is underexpressed in

and it is underexpressed in colorectal cancer

The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex

Defects in S1PR2 have been associated with congenital profound deafness

and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS

Histone deacetylation modulates chromatin structure

POLR3B Polyclonal Antibody, 20ul Mammalian Expression and it is underexpressed inPOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.