Neurofibromin Polyclonal Antibody, 100ul Capsule Filter The protein encoded by this

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan)

Phosphorylation at 'Ser-927' and 'Ser-932' are required for BTRC/BTRCP-mediated proteolysis

EphB4 (Htk)

53-regulated inhibitor of G2/M progression

The encoded protein acts as a homotrimer and is found in the cytoplasm

Neurofibromin Polyclonal Antibody, 100ul Capsule Filter The protein encoded by thisNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.