GKN2 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos This protein localizes to the

This protein localizes to the nuclear matrix

These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling| and they serve as targets for the small GTP binding proteins Cdc42 and Rac

including the alpha subunit of the inhibin A and B protein complexes

Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder

AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

GKN2 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos This protein localizes to theThe secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine 1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine 1 and regulates homeostasis of the gastric mucosa.