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FoxM1(Phospho-Ser35) Rabbit Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene are

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FoxM1(Phospho-Ser35) Rabbit Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene areThe protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3

Dynein axonemal light chain 1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella

The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis

It is also reported that the this protein functions as a demethylase to activate transcription| as DNA methylation causes gene silencing

This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression

FoxM1(Phospho-Ser35) Rabbit Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene areThe protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.

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