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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies which belongs to the adaptor

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies which belongs to the adaptorPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

which belongs to the adaptor complexes medium subunits family

It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3

This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons

The protein encoded by this gene regulates the DNA damage response through several different signaling pathways

Mutations in this gene cause Omenn syndrome

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies which belongs to the adaptorPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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