TRM6 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays NFKB1 encodes a 105 kD

NFKB1 encodes a 105 kD protein (nuclear factor kappa B subunit 1) which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

a calcium-binding epidermal growth factor-like domain

Mutations in COL18A1 are associated with Knobloch syndrome

A pseudogene has been identified on chromosome 1

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

TRM6 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays NFKB1 encodes a 105 kDThis gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase which is involved in the posttranslational modification that produces the modified nucleoside 1 methyladenosine in tRNAs. Modified 1 methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in