Tuberin(Phospho Tyr1571) Polyclonal Antibody, 100ul ssDNA Synthesis Localizing to the cell membrane

Localizing to the cell membrane

This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm

The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant

and partial evidence for several more variants exists

Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism

Tuberin(Phospho Tyr1571) Polyclonal Antibody, 100ul ssDNA Synthesis Localizing to the cell membraneMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.