TM55A Rabbit Polyclonal Antibody, 50ul sgRNA customized design SLC6A15 (solute carrier family 6

SLC6A15 (solute carrier family 6 member 15) encodes a member of the solute carrier family 6 protein family which transports neutral amino acids

Mutations in this gene are the cause of hyperlipoproteinemia| type 1D

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

cortactin is degraded in a caspase-dependent manner

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

TM55A Rabbit Polyclonal Antibody, 50ul sgRNA customized design SLC6A15 (solute carrier family 6TMEM55A catalyzes the degradation of phosphatidylinositol 4 5 bisphosphate (PtdIns 4 5 P2) by removing the 4 phosphate (Ungewickell et al. 2005