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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and is involved in mediating

SKU: 41156754948

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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and is involved in mediatingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system

This gene is highly expressed in testis and spleen

This gene and FGF3

for quality traceability

Diseases associated with C2orf40 include esophageal cancer

Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and is involved in mediatingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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