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EDG-2 Polyclonal Antibody, 100ul sgRNA customized design Defects in this gene are

SKU: 40978260357

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PLN141.00 PLN167.00

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EDG-2 Polyclonal Antibody, 100ul sgRNA customized design Defects in this gene areThe lysophosphatidic acid receptor 1 encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

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Description

Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM)

These pentameric receptors can bind acetylcholine| which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane

present throughout the cell cycle

Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers

The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family

EDG-2 Polyclonal Antibody, 100ul sgRNA customized design Defects in this gene areThe lysophosphatidic acid receptor 1 encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

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