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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation subcellular location:Localized to plasma membrane

SKU: 40953999481

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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation subcellular location:Localized to plasma membraneIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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subcellular location:Localized to plasma membrane coated pits

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Members of the F-box protein family| such as FBXL12| are characterized by an approximately 40-amino acid F-box motif

ZNF76 (Zinc Finger Protein 76) is a Protein Coding gene

IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation subcellular location:Localized to plasma membraneIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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