AES Polyclonal Antibody, 50ul Buffer Solutions Some haplotypes of this gene

Some haplotypes of this gene show a positive association with schizophrenia

Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity

Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter

Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10)

a transmembrane region and a highly conserved cytoplasmic tail

AES Polyclonal Antibody, 50ul Buffer Solutions Some haplotypes of this geneThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms