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APS Polyclonal Antibody, 100ul Recombinant Protein Expression RNA transport

SKU: 39726686330

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APS Polyclonal Antibody, 100ul Recombinant Protein Expression RNA transportThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

RNA transport

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage

45 µm pore size and PES membrane

Mutations in this gene are associated with Knobloch syndrome

The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family

APS Polyclonal Antibody, 100ul Recombinant Protein Expression RNA transportThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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