CENPL Polyclonal Antibody, 100ul DNA Oligo Synthesis Alternative splicing occurs at this

Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified

Studies suggest that this gene plays a role in organ development| wound healing| and tumor progression

Downregulation of this gene is associated with breast cancer

Another functional gene belonging to this family is located on chromosome 16

This gene encodes the beta-subunit protein

CENPL Polyclonal Antibody, 100ul DNA Oligo Synthesis Alternative splicing occurs at thisCENPL is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006)