Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Mutations in this gene have

Mutations in this gene have been associated with Johanson-Blizzard syndrome

|subcellular location:When uncleaved| it is predominantly cytoplasmic

endocytosis

while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin

SERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily

Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Mutations in this gene haveThe PID domain specifically binds to the Asn Pro Xaa Tyr(P) motif found in many tyrosine phosphorylated proteins. Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr 198 and Tyr 220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser 524 independently of reelin signaling. Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC FYN and ABL.