HSP27(Phospho Ser82) Polyclonal Antibody, 20ul Purification CASP8 and FADD-like apoptosis regulator

CASP8 and FADD-like apoptosis regulator encoded by CFLAR is a regulator of apoptosis and is structurally similar to caspase-8

The selenocysteine is encoded by the UGA codon that normally signals translation termination

May be one regulator of transcriptional events during hemopoietic development

Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD)

Interacts with HABP4 and KRT1

HSP27(Phospho Ser82) Polyclonal Antibody, 20ul Purification CASP8 and FADD-like apoptosis regulatorThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).