DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture TPD52L3 (tumor protein D52 like

TPD52L3 (tumor protein D52 like 3) encodes a member of the tumor protein D52-like family of proteins

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters

The external domain mediates cell attachment to the extracellular matrix molecule vitronectin

PLAGL1 encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture TPD52L3 (tumor protein D52 likeThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and