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TPP1 Polyclonal Antibody, 50ul Dry Bath The protein encoded by this

SKU: 39018558330

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TPP1 Polyclonal Antibody, 50ul Dry Bath The protein encoded by thisThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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Description

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state

Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described

Cathepsin A possesses deamidase

Overexpression of this gene leads to elevated expression of several GADD family genes

TPP1 Polyclonal Antibody, 50ul Dry Bath The protein encoded by thisThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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