IFIX Rabbit Polyclonal Antibody, 20ul Electronic Pipette 2005 [PubMed 16199532])

2005 [PubMed 16199532])

This gene was originally isolated based on its deletion in a medulloblastoma cell line

AKR1B1 encodes a member of the aldo/keto reductase superfamily

a chemokine which specifically mediates monocyte chemotaxis

This gene shares both structural and functional similarities with the dystrophin gene

IFIX Rabbit Polyclonal Antibody, 20ul Electronic Pipette 2005 [PubMed 16199532])The protein encoded by this gene belongs to the HIN 200 family of interferon inducible proteins that share a 200 amino acid signature motif at their C termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and