TCF-3 Polyclonal Antibody, 100ul[BT-AP08891] Endonucleases & Exonucleases Neural retina leucine zipper is

Neural retina leucine zipper is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function

which is required for ubiquitin-mediated degradation of cell cycle G1 regulators

Mutations in this gene are associated with a variety of human cancers

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but lacks several residues that are critical for catalytic activity

TCF-3 Polyclonal Antibody, 100ul[BT-AP08891] Endonucleases & Exonucleases Neural retina leucine zipper isTCF3 encodes a member of the E protein (class I) family of helix loop helix transcription factors. E proteins activate transcription by binding to regulatory E box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA binding (class IV) helix loop helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development.