CRGC Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Interacts also with SIAH1 which

Interacts also with SIAH1 which promotes targeting for degradation

GO annotations related to this gene include protein phosphatase inhibitor activity

Expressed mainly in the liver and in serum (at protein level)

6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck

CRGC Rabbit Polyclonal Antibody, 100ul Drying & Desiccation Interacts also with SIAH1 whichThis gene encodes a member of the beta gamma crystallin family of proteins. Crystallins constitute the major proteins of vertebrate eye lens and maintain the transparency and refractive index of the lens. This gene and several family members are present in a gene cluster on chromosome 2. Mutations in this gene have been shown to cause multiple types of cataract including Coppock like cataract and zonular pulverulent cataract among others.