TRAF6 Polyclonal Antibody, 100ul Pathway and Network Analysis Functions as a host factor

Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins

Alternatively spliced transcript variants that encode different isoforms have been observed for this gene

one within the cell and a second after secretion into the blood

Defects in PEX5 are a cause of neonatal adrenoleukodystrophy (NALD)

NUMA1 encodes a large protein that forms a structural component of the nuclear matrix

TRAF6 Polyclonal Antibody, 100ul Pathway and Network Analysis Functions as a host factorTNF receptor associated factor 6 encoded by TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll IL 1 family. Signals from receptors such as CD40, TNFSF11 RANCE and IL 1 have been shown to be mediated by this protein.