PA26 Polyclonal Antibody, 50ul Palm Micro Centrifuges Alternative splicing of this gene

Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties

as well as other neuronal ceroid-lipofuscinosis (CLN) genes

Pseudogenes related to this gene are located on chromosomes 1

This complex is a heterotetramer composed of two large

This nuclear enzyme is involved in processes such as chromosome condensation

PA26 Polyclonal Antibody, 50ul Palm Micro Centrifuges Alternative splicing of this geneSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized