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Neu Polyclonal Antibody, 20ul[BT-AP05902] Reagent Reservoirs It is also a substrate

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Neu Polyclonal Antibody, 20ul[BT-AP05902] Reagent Reservoirs It is also a substrateERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

It is also a substrate for the cyclic AMP-dependent protein kinase

Four propeptides

In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation

BCL6 is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL)

Three transcript variants encoding two different isoforms have been described

Neu Polyclonal Antibody, 20ul[BT-AP05902] Reagent Reservoirs It is also a substrateERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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