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OVOL2 Polyclonal Antibody, 20ul Thermal Control an autosomal dominant pre-malignant disease

SKU: 3621733122

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OVOL2 Polyclonal Antibody, 20ul Thermal Control an autosomal dominant pre-malignant diseaseThis gene encodes a member of the evolutionarily conserved ovo like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N and C terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that

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Description

an autosomal dominant pre-malignant disease that usually progresses to malignancy

and cell volume control

namely HM74A and HM74B (also known as simply HM74)

result from single point mutations of the glycophorin C gene

Expressed in spleen

OVOL2 Polyclonal Antibody, 20ul Thermal Control an autosomal dominant pre-malignant diseaseThis gene encodes a member of the evolutionarily conserved ovo like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N and C terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that

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