TNKS2 Polyclonal Antibody, 100ul Enzymes & Activity Assays Guanine nucleotide exchange factors (GEFs)

Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP

GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa

The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol

Component of the NF-kappa-B p65-p50 complex

and also familial hypertrophic cardiomyopathy

TNKS2 Polyclonal Antibody, 100ul Enzymes & Activity Assays Guanine nucleotide exchange factors (GEFs)Catalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4 GLUT4 vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM: ADP ribosylated ( auto).,Contains 1 PARP catalytic domain.,Contains 1 SAM (sterile alpha motif) domain.,Contains 15 ANK repeats.,subcellular