TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Through its disintegrin-like domain| this

Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3

The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form

Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

their beta chains are unique and confer biological specificity

TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Through its disintegrin-like domain| thisTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,