FoxL1 Polyclonal Antibody, 50ul Lysosome Misincorporation of oxidized nucleoside triphosphates

Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration

activation of a MAP kinase signaling pathway

UV irradiation

NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators

and knockout studies in mice

FoxL1 Polyclonal Antibody, 50ul Lysosome Misincorporation of oxidized nucleoside triphosphatesFOXL1 encodes a member of the forkhead winged helix box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis.