JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The encoded protein consists of

The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain

disease:Expressed in a variety of skin disorders| including allergic contact dermatitis| lichen planus and mycosis fungoides

it lacks domain VI

Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells

this protein is reported to associate with centrosomes in a microtubule-dependent manner

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The encoded protein consists ofThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).