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SCRIB Polyclonal Antibody, 50ul Cell Culture Mutations in this gene are

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SCRIB Polyclonal Antibody, 50ul Cell Culture Mutations in this gene areThis gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C terminus of E6. Two alternatively spliced transcript variants that encode different protein

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Description

Mutations in this gene are associated with a variety of human cancers| including hereditary cancers such as Li-Fraumeni syndrome

Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

SEMA3C (Semaphorin 3C) is a Protein Coding gene

subcellular location:Concentrates at the leading edge of cells

SCRIB Polyclonal Antibody, 50ul Cell Culture Mutations in this gene areThis gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C terminus of E6. Two alternatively spliced transcript variants that encode different protein

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