HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis FEV is fused to the

FEV is fused to the Ewing sarcoma (EWS) gene following chromosome translocations

Expression of antizymes requires +1 ribosomal frameshifting

the protein binds to iron-responsive elements (IREs)

Mutations in this gene have been associated with left-right axis malformations| particularly in the heart and lungs

Belongs to the CYFIP family

HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis FEV is fused to theEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.