p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes most notably the t(9|22) translocation

most notably the t(9|22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR| MIM:151410)

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

2001 [PubMed 11242035])

The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes

and Biacore surface resonance analysis

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes most notably the t(9|22) translocationTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni