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CD34 Polyclonal Antibody, 50ul Serum Overexpression of this gene suppresses

SKU: 35110989791

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SEK185.00 SEK210.00

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CD34 Polyclonal Antibody, 50ul Serum Overexpression of this gene suppressesCD34 molecule encoded by CD34 may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for CD34.

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Description

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

It also functions in the regulation of JUN oncogene expression

hydrolyzing O-glycosyl compounds and beta-galactosidase activity

platelet-type and bernard-soulier syndrome

While adducins alpha and gamma are ubiquitously expressed

CD34 Polyclonal Antibody, 50ul Serum Overexpression of this gene suppressesCD34 molecule encoded by CD34 may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for CD34.

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