NGFR p75 Monoclonal Antibody, 100ul Sample Library Tubes and was first identified as

and was first identified as being upregulated in psoriasis tissue

suggesting a role as a transcription factor

Two transcript variants encoding distinct isoforms have been identified

The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities

This heterodimer binds E-box enhancer elements upstream of Period (PER1| PER2| PER3) and Cryptochrome (CRY1| CRY2) genes and activates transcription of these genes

NGFR p75 Monoclonal Antibody, 100ul Sample Library Tubes and was first identified asNerve growth factor receptor contains an extracellular domain containing four 40 amino acid repeats with 6 cysteine residues at conserved positions followed by a serine threonine rich region, a single transmembrane domain, and a 155 amino acid cytoplasmic domain. The cysteine rich region contains the nerve growth factor binding domain.