FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases MAPT gene mutations have been

MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy

the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP)| beta (CEBPB) and may play a role in inflammation

Multiple splice variants encoding different isoforms have been found for this gene

FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases MAPT gene mutations have beendisease: Defects in F8 are the cause of hemophilia A (HEMA)