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VHL(Phospho Ser68) Polyclonal Antibody, 50ul Antibody Humanization Eukaryotic translation initiation factor 2-alpha

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VHL(Phospho Ser68) Polyclonal Antibody, 50ul Antibody Humanization Eukaryotic translation initiation factor 2-alphaVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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Description

Eukaryotic translation initiation factor 2-alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress

is found on many blood cells where it serves to anchor proteins to the cell surface

The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons

In vertebrates| sister chromatid cohesion is released in 2 steps via distinct mechanisms

Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts| cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI)

VHL(Phospho Ser68) Polyclonal Antibody, 50ul Antibody Humanization Eukaryotic translation initiation factor 2-alphaVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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