IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling LRRC41 is a Protein Coding

LRRC41 is a Protein Coding gene

The conserved helix-loop-helix ubiquitous kinase

The encoded protein contains six extracellular cadherin domains| a transmembrane domain| and a cytoplasmic tail differing from those of the classical cadherins

as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis

In the nucleus

IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling LRRC41 is a Protein CodingThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been