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INTS2 Polyclonal Antibody, 50ul Cell Culture Dishes These zinc finger domains

SKU: 34455763679

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INTS2 Polyclonal Antibody, 50ul Cell Culture Dishes These zinc finger domainsINTS2 (integrator complex subunit 2) is a subunit of the Integrator complex, which associates with the C terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3 prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690).

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Description

These zinc finger domains

This subunit can be phosphorylated by the activated catalytic subunit

including Wilm's tumor

and inhibited by GTPase activating proteins (GAPs)

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I

INTS2 Polyclonal Antibody, 50ul Cell Culture Dishes These zinc finger domainsINTS2 (integrator complex subunit 2) is a subunit of the Integrator complex, which associates with the C terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3 prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690).

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