Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research May be required for chromosome

May be required for chromosome segregation during cell division

and it is required for the association of centromere-associated protein E with the kinetochore

Interacts with RNF43

Interleukin-32 induces the production of TNFalpha from macrophage cells

The first step involves recognition of the TATA element by the TATA-binding subunit (TBP

Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research May be required for chromosomeMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.