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MRGRD Polyclonal Antibody, 100ul Immunoassays This receptor can be activated

SKU: 34229211907

4.3
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MRGRD Polyclonal Antibody, 100ul Immunoassays This receptor can be activatedMay regulate nociceptor function and or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta alanine. Beta alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta alanine decreases forskolin stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G protein G(q) and G(i).,Belongs to the G protein coupled

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Description

This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L)| and transduces an apoptosis signal

Among its related pathways are MAPK signaling pathway and p38 MAPK signaling pathway (Pathway Interaction Database)

q11) with immunoglobulin gene regions

PTM:Phosphorylated by GSK3B

Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects

MRGRD Polyclonal Antibody, 100ul Immunoassays This receptor can be activatedMay regulate nociceptor function and or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta alanine. Beta alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta alanine decreases forskolin stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G protein G(q) and G(i).,Belongs to the G protein coupled

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