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CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays This inhibitory effect is selective

SKU: 34036203811

4.4
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CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays This inhibitory effect is selectiveThe protein encoded by ACKR4 is a member of the G protein coupled receptor family, and is a receptor for C C type chemokines. Atypical chemokine receptor 4 has been shown to bind dendritic cell and T cell activated chemokines including CCL19 ELC, CCL21 SLC, and CCL25 TECK. A pseudogene of ACKR4 is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.

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Description

This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts

The protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1

Preferentially binds to alpha-2

Mutations in this gene have be associated with autosomal recessive Segawa syndrome

and peripheral blood

CCRL1 Polyclonal Antibody, 50ul[BT-AP01326] Cellular Function Assays This inhibitory effect is selectiveThe protein encoded by ACKR4 is a member of the G protein coupled receptor family, and is a receptor for C C type chemokines. Atypical chemokine receptor 4 has been shown to bind dendritic cell and T cell activated chemokines including CCL19 ELC, CCL21 SLC, and CCL25 TECK. A pseudogene of ACKR4 is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.

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