Mouse Clusterin, CLU ELISA Kit , 96T Adenovirus Packaging Mutations in this gene are

Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)

but currently do not represent full-length sequences

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation

Multiple transcript variants have been found for this gene

ubiquitin aldehyde binding 2 contains an OTU domain and binds Ubal (ubiquitin aldehyde)

Mouse Clusterin, CLU ELISA Kit , 96T Adenovirus Packaging Mutations in this gene areFunctions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress induced aggregation of blood plasma proteins (By similarity). Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation prone LYZ variants (in vitro) (PubMed: 14741101). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8