M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller The N-terminal region is required

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

encoding nearly 900 genes

It is predominantly expressed in the pituitary gland

subunit:Interacts with beta-1 integrin subunit

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller The N-terminal region is requiredThe protein encoded by this gene is the receptor for colony stimulating factor 1 a cytokine which controls the production differentiation and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF