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ZHX2 Polyclonal Antibody, 20ul Buffers & Solutions It inhibits signal transduction by

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ZHX2 Polyclonal Antibody, 20ul Buffers & Solutions It inhibits signal transduction byThe members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor Y (NF YA) and contain two C2H2 type zinc fingers and five homeobox DNA binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

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Description

It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits

Heterodimers consisting of alpha and gamma subunits have also been described

A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters

It shares limited sequence similarity with iron-only bacterial hydrogenases

Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS)

ZHX2 Polyclonal Antibody, 20ul Buffers & Solutions It inhibits signal transduction byThe members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor Y (NF YA) and contain two C2H2 type zinc fingers and five homeobox DNA binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

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